Identification of atypical features is important in the treatment of depression for both treatment selection and prognosis, especially when initial measures prove ineffective. The concept of atypical depression has evolved over many years, and now it appears timely for a further revision.

Atypical Depression in the 21st Century: Diagnostic and Treatment Issues

 What Works for Psychiatrists in Community and Institutional Settings 

Developmental Disabilities From Childhood to Adulthood:

Reflecting on my internship year evokes anxious feelings, despite the fact that I am separated from it by time, distance, and hundreds of positive experiences.

Asking the Right Question

 Expansion of age-appropriate developmental psycho-therapeutic services must become a top public health priority to make these treatments more widely available to young children and to capture the potential greater benefit of the earliest possible intervention for mental disorders.  

Psychiatric Assessment and Treatment in Preschool Children

 Pushing the edge of our understanding into the murky world of association cortex only means that future experiments will be trickier to interpret.  

The Neurobiology of Conscious Intent

 . . . her fixed state is one of intent though fruitless searching. She is inactive not because she is too lazy to work but because work has become meaningless to her; her energy is paralyzed not by sleep but by thought.” 

Is Major Depression “Adaptive”?

 Richard Berlin,M.D.: “There is something about the condensed pressure of poetry that feels very natural to me.” 

New Year’s Eve

 NIMH is shifting away from current-generation treatments and toward preclinical drug development and early-phase clinical pharmacology, according to the institute’s director and a workgroup co-chair. 

NIMH Shifts Focus to Molecular Origins of Mental Illness

ECT, like abortion, is surrounded by controversy and strong opinions on both sides. Fortunately, for those of us who practice ECT, the discussion is not quite as heated nor the risks as high as for our colleagues in ob-gyn.

Electroconvulsive Therapy: The Second Most Controversial Medical Procedure

Emerging research suggests that some individuals with particular types of substance use and abuse may be more likely to engage in suicidal behaviors. For example, those who use opiates, cocaine, or sedatives may have a noticeably higher risk of suicide than those who use other drugs.

The Link Between Substance Abuse, Violence, and Suicide

What goes on in the minds of those who attempt suicide? Here: a psychologist who explores the myths that surround suicide notes "We need to get it in our heads that suicide is not easy, painless, cowardly, selfish, vengeful, self-masterful, nor rash."

Psychiatric Times Vol 28 No 1