The role of subtyping and bipolarity in TRD was discussed in Part 1 of this 2-part article. Here we review a number of the most common confounding factors of TRD but limit our scope to comorbidities that can be directly addressed and treated by psychiatrists.

Confounding Factors in Treatment-Resistant Depression (Part 2): Comorbidities and Treatment Resistance

Here we discuss how advancements in anesthesia techniques and ECT procedures make ECT more comfortable and tolerable for patients.

Anesthesia Advances Add to Patient Comfort in ECT

It appears that the risk is greater with antidepressant use during late pregnancy but may be elevated with use during early pregnancy as well.

Antidepressants and Persistent Pulmonary Hypertension of the Newborn

Ongoing advances in functional brain imaging will permit studies on postulated roles of magnetic fields, biophotons, and macroscopic highly coherent quantum field effects on normal brain functioning and mental illness.

Initiatives in Integrative  Mental Health

Psychotherapy is a rubric--an umbrella under which a vast array of differing interventions exist. Its diverse forms are supported by different ideologies and vocabularies.

On the Essence of Psychotherapy

Effective personalized treatment recognizes bipolar disorder as a biopsychosocial disorder, but mood-stabilizing medications are the backbone of treatment. These medications fall into 3 categories: lithium, antikindling/antiepileptic agents, and second-generation antipsychotics.

Effective Personalized Strategies for Treating Bipolar Disorder

Wild Night, after the cops came to shut the music down, after friends and family were headlights pointed toward home...

After the Party

Two recent publications provide clinically relevant information about the risk to benefit ratio of antidepressants for the treatment of MDD in youths, adults, and the elderly.

Antidepressants: Risk vs Benefit in Depression

Should we accept the analysis of a journalist who has not treated a patient or implemented a study and reaches conclusions that run counter to well-established practice guidelines?

The Occupation of Psychiatry?

Clinicians tell patients that we will keep their information private and then turn around and put it into an electronic health record that can do just the opposite. . . . Putting confidential information into an electronic health record can be like putting it up on a billboard.

Electronic Health Records and Patient Privacy-An Oxymoron?

Of the 3 informative articles included in this special geriatric collection, 1 offers a perspective on the treatment of depression that does not focus on somatotherapy. The others remind us of 2 additional geriatric Ds of importance: drugs and driving.

Introduction: Dementia, Delirium, Depression, Drugs, and Driving

This article provides a practical overview of the available evidence-based treatment and discusses circumstances in which certain interventions may be preferred over others.

Psychotherapy for Late-Life Depression

As we are faced with a growing population of older adults, a better understanding of the issues that they confront is crucial.

Substance Abuse in Aging and Elderly Adults

Medical professionals may be reluctant to initiate a discussion about driving with older patients in anticipation of a negative impact on the physician-patient relationship.

Psychiatric Times Vol 29 No 8