What to do once treatment-resistant depression is established based on risk factors and exclusion of other conditions? Insights here-and a treatment algorithm.

Factors That Predispose Patients to Treatment-Resistant Depression

Because cognitive and negative symptoms have the greatest impact on overall recovery, interdisciplinary strategies that target these symptoms are necessary. This article offers details. 

Management of Treatment-Refractory Schizophrenia

The discovery that a single IV infusion of low-dose (subanesthetic) ketamine exerts rapid antidepressant effects constitutes an expansion in our understanding of the neurobiology of depression and provides new avenues for drug development. 

Ketamine for Treatment-Resistant Unipolar Depression: Current Evidence

It seems to this psychiatrist that a significant cohort of his colleagues conduct their practices in what might best be described as an “underground economy”: a system of services and charges disconnected from the conventional constructs by which these activities are presumably measured.

Psychiatry’s Underground Economy

If you're up for a little ancient humor, you'll love this original translation of an ancient Babylonian text in which a physician is jilted on a fee, then is further embarrassed in his efforts to collect it. 

How I Got Schooled in Ancient Psychiatry

Having just completed my first year as an attending physician, I realize that there is simply nothing that prepares you to be an attending-except being an attending. 

My Anniversary

Of all the transferences that emerge in the consultation room, sexual feelings are by far the least talked about and the most challenging for therapists to manage. This author talks about erotic transferences here.

Sexualized Transference in Older Adults

Genius and madness: does one phenomenon cause the other-or do both share a common underlying factor or mechanism? How are geniuses able to accomplish “creative fits”? The author explores both questions.

The Association Between Major Mental Disorders and Geniuses

Why do patients with eating disorders resist treatment? How can the clinician address resistance? 

Patient Resistance in Eating Disorders

Boyhood’s power-and poignance-centrally derives from one’s visceral experience of the authentic signatures of time on its actors’ features and forms . . . life cycle theory made flesh as it were. 

Boyhood

To combat opiate abuse and its dire consequences, drug makers have developed a number of strategies--which are detailed here.

Roadblocks to Opiate Abuse

Glutamatergic models have led to greater understanding of the causes of social and occupational disability in schizophrenia, and thus have provided new targets for remediation and compensation strategies. 

Glutamate and Schizophrenia: From Theory to Treatment Implications

This sunflower at the 9/11 Memorial said that a ray of sunshine remains, and that life blooms anew, in spite of the losses. 

Rainy Day Sunflower at 9/11 Memorial

What effect does exposure to violence in video games have on behavior? These authors examine the evidence.

Violence, Crime, and Violent Video Games: Is There a Correlation?

Psychiatric Times welcomes Drs Allan Tasman and Michelle Riba as our new Editor and Deputy Editors in Chief.

At Psychiatric Times, a Changing of the Guard

It's always a brain tumor when I have a headache. “Don’t be crazy,” I tell myself, “You’re just inventing a doctor-mind catastrophe.”

It’s Always a Brain Tumor

People feel free to post comments on social media sites that they would never dare say to someone’s face. The cure, if only a partial one, is to get out of social media and to start living a real life. What is your opinion on this issue?

Social Media Use: A Closer Look at the Real Meaning of Friends

If we didn't so stigmatize the severely mentally ill, we would feel an urgent responsibility to rescue them immediately from prison and homelessness.

Stigmatizing And Shunning The Severely Ill

Military veterans are ubiquitous in our practices and in our lives. The impact of the past several years of armed conflict is greater than many think-and much greater than simply the number of veterans in your practice or your community.

Military and Veteran Mental Health: Why Should Psychiatrists Care?

The “story behind the story” is not the over-prescription of antidepressants-though it happens-but the under-availability of optimal treatment.

 Are Antidepressants Really “Over-Prescribed” in the US?

Imagine an end to psychiatric episodes that threaten job and family, no more hospitalizations, and a chance for a long life not cut short by mental illness and its complications. What can we take away from the HIV/AIDS story for the treatment of mental illness? 

Vol 31 No 9