The Psychopharmacology of Depression: Strategies, Formulations, and Future Implications
Recent findings suggest that the magnitude of efficacy for most antidepressants compared with placebo may be more modest than previously thought.
Major Depressive Episode: Is It Bipolar I or Unipolar Depression?
Since the choice of treatments for a primary bipolar I disorder major depressive episode versus a unipolar major depressive episode are significantly different, this information will help guide clinicians in how to proceed.
Pseudobulbar Affect Versus Depression: Issues in Diagnosis and Treatment
The most challenging aspect of pseudobulbar affect is differentiating it from depression. Episodes of uncontrollable, sudden, and even inappropriate emotions may point to neurologic or psychiatric conditions.
Addressing Depression: The World’s Largest Health Problem
Despite the scope and magnitude of rising rates of depression and suicide, the field of psychiatry may be witnessing a turning point.
Psychotherapeutic Interventions for Depression: Which Work Best?
In considering how best to disseminate the many psychotherapeutic techniques to practicing clinicians, the author reviews findings and changes to guidelines on depression treatments.
Multimodal Markers and Biomarkers of Treatment
The use of biomarkers to assist with optimizing treatment decisions for depression has been receiving increasing attention. Here is an overview of the challenges and barriers that must be overcome before therapeutic markers can effectively be utilized in practice.
A Historical Perspective on Suicide
Walter Benjamin’s suicide is especially interesting as a bridge from the Freudian psychosocial era of hysteria-neuroses to the current era of the borderline-narcissist.
10 Meditations on Succeeding—and Flourishing
If we fail to cultivate and exercise virtues such as wisdom, curiosity, intellect, aesthetic sensitivity, compassion, empathy, and generosity, we fail to exemplify human flourishing.
Babble on Revisited
Bingeing on news about the latest White House rumpus has escalated exponentially since the election. Whatever their political views, patients are haunted by an inchoate sense that the wheels are coming off the car, with nary a mechanic in site.
Millard Salter’s Last Day
In this novel, we join New York consultation-liaison psychiatrist Dr Millard Salter for what he intends to be his final day on earth.
Black and White and Red All Over
Where are the crusading editorial boards who decide that the inadequacy of mental health care is such a public health emergency that ongoing investigative journalism is needed?
Addressing the Challenges of Treatment Resistant ADHD in Adults
This CME identifies the sources of treatment-resistant ADHD in adults and focuses on preventing misdiagnosis and optimizing treatment.
Cognitive Effects of MIN-101 in Patients With Schizophrenia and Negative Symptoms
A novel compound holds promise for addressing cognitive deficits in schizophrenia.
Suicides and Psychiatrists
Like the song New York, New York, if we can succeed in reducing suicide in physicians, we can do it anywhere.
Silver Linings After Abuse and Neglect
The neuroprotective role of resilience in patients with schizophrenia who experienced early childhood trauma is evaluated in this brief update.
Mental Illness, Civil Liberty, and Common Sense
More than any other medical specialty, we sometimes feel compelled, and empowered, to treat patients against their will. With this comes two great responsibilities.
Will the AMA Heed Its Own Ethics Council Regarding Assisted Suicide?
The thorny issue of “end-of-life care” is likely to remain controversial in the US, with physicians themselves holding a wide variety of views.
5 Ways to Ask About Hypomania
Hypomania is critical to rule out, but hard to pin down. In part 1 of this 2-part series, Dr. Aiken shares his top pearls for making the diagnosis.
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