Sleep-Wake Disorders

Sleep disorders represent a significant problem in patients with Alzheimer disease. Here: assessment strategies and a review of drug and non-drug interventions.

Sleep-related problems are among the most disabling consequences of TBI, with multiple influences: impairment of neuronal plasticity, metabolomic alterations, loss of vascular homeostasis, and disruption of the blood-brain barrier. The authors take a close look.

Circadian components are profound in depressive disorders, such seasonal affective disorder. This article introduces a course to be given at this year’s APA Meeting in Toronto, on melatonin and light treatment.

The human condition is such that all of us may be vulnerable to seasonal affective disorder. If placed in an environment sufficiently deprived of light we would all develop a reversible syndrome of major depression.

In what psychiatric disorder, if any, has wake therapy been useful to alleviate symptoms? Take the quiz and learn more.

In this video, Dr Karl Doghramji, describes the various agents available for managing sleep disorders and discusses the adverse effects associated with over-the-counter, nutraceutical, and prescription sleep aids.

Chronobiology-the science of daily (circadian), monthly, tidal, and seasonal rhythms-has undergone exponential growth in the past decade, with major discoveries at the molecular and neuroanatomic level.

Most patients with psychiatric diagnoses present with sleep disturbances that can have as great an impact on health-related quality of life as the mental illness itself. Here are tips on treatment and chronotherapeutic applications for major depression and other disorders.

What's new in sleep medicine? The latest developments in both new and novel approaches to treating sleep disorders.

Depression is a frequent psychiatric comorbidity among patients with restless leg syndrome. The case presented here illustrates the importance of evaluating for RLS symptoms in patients with major depressive disorder who complain of insomnia.

Sleep-disordered breathing signs and symptoms overlap with mood, anxiety, and other psychiatric illnesses. In some cases, they may masquerade as these disorders, but SDB can also provoke and/or exacerbate other psychiatric conditions. Signs, risk factors, and clinical features in this Tipsheet.

Narcolepsy, cataplexy: symptoms are broad and associated with a range of medical and psychiatric comorbidities. Here: diagnostic and treatment strategies and a look at the BOND study.

A book that may help doctors, as well as their patients, better understand how they tick, literally, in our 24/7 society, and find a balance between difficult temporal demands and somatic and mental health.

More than half of all patients with psychiatric disorders report disturbances of sleep and wakefulness. "Sleep disorders are associated with impaired daytime function and predict a heightened future vulnerability to psychiatric disease. They also diminish life span.” Details from an expert here.

This brief review addresses what is currently known about sleep problems in women. The main focus is on sleep issues that are particularly relevant to reproductive stages in a woman’s life cycle and therefore potentially linked to reproductive and/or hormonal factors.

Astrocytic signaling to adenosine receptors results in the robust reduction of depressive-like behaviors associated with sleep deprivation.

Psychiatric disorders, such as primary sleep disturbances, depression, substance abuse, mania, sexually inappropriate behaviors, and psychosis, can complicate the care of patients with dementia.

Insomnia-a sleep disorder that can pose impairments far more debilitating than than problems with cognition (eg, difficulty processing, unclear thinking).

The goal of this article is to improve recognition of comorbid psychiatric and movement disorders and to help the reader formulate a management strategy using a multidisciplinary approach.

What are the options for treating major depressive disorder in children and adolescents? This case offers readers a chance to give their feedback and to interact with the authors, who will present teaching points based on your comments.

What is sleep normally and what are the primary factors that regulate sleep? Understanding that the primary factors that regulate the sleep wake cycle are homeostatic and circadian will help clinicians assess sleep problems in patients.

Sleep-disordered breathing is common in patients with mood and anxiety disorders. This article explores the implication for practicing psychiatrists whose patients have sleep disorders.

Melatonin has a role in psychiatric illness and the treatment of circadian rhythm sleep disorders, insomnia, and comorbid depressive disorders.

Although the purpose of sleep continues to be the subject of much debate, few would argue that a well-functioning sleep-wake cycle is essential for good health.

Knowledge of how different antidepressants are likely to affect parameters of sleep can provide an important basis for selecting an appropriate antidepressant drug among the roughly 2 dozen marketed options to meet the needs of depressed patients.