Author | Thomas R. Kosten, MD


Are We Making Any Progress in Treatment and Attitudes?

March 23, 2020


How much progress has been made in the area of substance use disorders in the last 40 years?

The Opioid Epidemic Settlements: Who Will Benefit?

October 10, 2019


Judgements and settlements are starting in Oklahoma against various pharmaceutical companies for their alleged roles in that state’s opioid crisis. Who would be the beneficiaries of these funds?

Innovative Non-Opioids for Chronic Pain: Ketamine and Cannabidiol

October 08, 2019


This overview addresses two medications for analgesia of chronic benign pain, both of which have substance abuse risks themselves.

Cannabinoids for Chronic Pain: An Opioid Alternative?

August 20, 2019


The cannabinoids (particularly CBD) have been hailed as non-addictive solutions to using escalating doses of opioids for chronic pain. More in this research update.

Revisiting the Hallucinogenic Potential of Ketamine

June 26, 2018


An exploration of findings from contemporary research that hint at the unexplored hallucinogenic potential of ketamine and considerations for future investigation.

Q&A: Clinical Challenges in Substance Use Disorders

September 17, 2017


What's the optimal strategy toward recovery from opioid use disorder? Which treatment for nicotine addiction has the most favorable adverse-effect profile?

New Insights on Substance Use Disorders

July 28, 2017


A clinical collection on addiction treatment, ADHD and SUDs, important drug indications, vaping, cannabis use, benzodiazepines, the perils of self-medicating and other topics relevant to practicing psychiatrists.

Update on the Opioid Wars

July 24, 2017


Significant progress has been made in containing the opioid epidemic, but new threats loom. Thomas Kosten, MD, an addiction psychiatrist, takes a brief look.

Introduction: Cautions, Considerations, and Treatment Strategies

June 30, 2017


The Chair of a Special Report on substance abuse disorders describes the highlights of 6 articles in the series.

Emerging Treatments and Pharmacogenetics for Cocaine Use Disorder

May 31, 2016


There are no FDA-approved pharmacotherapies for cocaine use disorder. Here: a review of the off-label use of promising medications for this addiction.