Advice for Clinicians Considering an Interventional TRD Practice

This episode, titled ‘Advice for Clinicians Considering an Interventional TRD Practice,’ features panelists discussing the following critical questions:

What would you tell a colleague who is on the fence about opening an esketamine practice for treatment-resistant depression?

What challenges should clinicians expect when caring for a community of patients with treatment-resistant depression?

Led by the moderator, the panelists examined the rewards and demands of interventional care. Dr. Yudkoff describes the work as deeply gratifying because these treatments can act quickly and reliably where others have not, while cautioning colleagues to prepare for prior authorizations, inconsistent definitions of TRD, and the emotional weight of supporting patients in acute distress. He encourages those with the time and resilience to move forward, reassess at regular intervals, and lean on their partners. Gene Dolgin adds that this care depends on a true partnership between clinical and operational teams.

Throughout the conversation, the experts provide a comprehensive reflection on the field and the factors that may shape how clinicians approach care moving forward.

In the next episode, ‘Running a Sustainable Esketamine Treatment Center for TRD,’ panelists will continue their discussion on treatment-resistant depression and highlight the operational decisions behind a sustainable center and the lessons they have learned.