Mini-quiz: Alcohol Use Disorders

Which benzodiazepine is conjugated and renally cleared and therefore safer to use in patients with hepatic disease? Take the quiz, below.

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Answer: A. Lorazepam.

Patients with a history of complicated alcohol withdrawal syndrome should be treated with a standing benzodiazepine taper during detoxification. For patients with hepatic disease, benzodiazepines that are conjugated and renally cleared (eg, lorazepam) should be used instead of those metabolized by the liver.

For more on this topic, please see "Alcohol Disorders: Practical Tips From New Research," from which this quiz was adapted.

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