Your Mother Was Right . . .

Key Takeaways

• Omega-3 polyunsaturated fatty acids delivered via fish oil were associated with reduced conversion from subthreshold psychotic symptoms to overt psychotic disorder in youth.
• The intervention is positioned as a nonpharmacologic, potentially disease-modifying strategy for individuals at clinical high risk for psychosis.
• Absence of drug-like adverse effects was emphasized, contrasting with tolerability and safety limitations that can complicate early antipsychotic use.
• The results support additional studies to validate efficacy, define optimal dosing and duration, and clarify mechanisms in prodromal psychosis.