How Best to Make the Switch to Clozapine
What’s the optimal approach for patients with treatment-resistant schizophrenia?
View the slides in PDF format. Also see: Impaired Glucose Homeostasis in First-Episode Schizophrenia.
Clozapine is the “gold-standard” antipsychotic for treatment-resistant schizophrenia.
What are potential risks of antipsychotic discontinuation?
Takeuchi and colleagues[2] hypothesized that there would be no differences in efficacy or tolerability between the 2 strategies.
The primary findings were significant improvements in psychopathology upon switching to clozapine.
These preliminary findings suggest that either strategy could be used by prescribers based on clinical judgment.
