Mini Quiz: Antipsychotic Polypharmacy

Which treatments have proven to be efficacious in meta-analyses as augmentation of clozapine in reducing positive symptoms of schizophrenia? The answer might surprise you.

Hundreds of randomized controlled trials have been conducted to test the efficacy of the multiple forms of polypharmacy in various symptom domains of psychoses.

Which of the following has proven to be efficacious in meta-analyses as augmentation of clozapine in reducing positive symptoms?

A. Topiramate

B. Lithium

C. Risperidone

D. Venlafaxine

E. None of the above

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