Common Augmentation Strategies for Depression: Findings Show Lack of Evidence
It is estimated that at least half of persons who begin antidepressant treatment will not respond to monotherapy.
Antidepressants Versus Placebos: Meaningful Advantages Are Lacking
The slight difference between antidepressant and placebo has been referred to as a "dirty little secret" by researchers, a secret that was believed by FDA officials to be "of no practical value."
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