
How much of the beneficial effects of anti-depressant medications can be ascribed to the placebo effect? Irving Kirsch, Ph.D., and Guy Sapirstein, Ph.D., addressed this important question in a recent study that appeared in the first volume of the American Psychological Association's online journal, Prevention and Treatment (June 26,1998). Although their methodology and conclusions have met with some controversy, it would be imprudent to invalidate the study and its hypothesis.