
Transcranial direct current stimulation delivery systems differ from one another in design, action, and results. One has been shown to be significantly better than sham treatment for bipolar depression. What does this mean for clinical practice?


Transcranial direct current stimulation delivery systems differ from one another in design, action, and results. One has been shown to be significantly better than sham treatment for bipolar depression. What does this mean for clinical practice?

ECT has been found effective in mitigating the deleterious consequences of SIB.

Lamotrigine’s favorable tolerability is a welcome advance for patients with bipolar disorder. The danger it poses is at the start of treatment, when its mood-lifting effects can easily be waylaid by the eruption of a rash.

This statin shows promise in reducing symptoms of bipolar disorder and depression. Still, one must be cautious and think through the treatment plan for each patient.

Recent studies have demonstrated the wide-reaching adverse effects of being bullied in childhood. These effects range from impaired academic performance to interest in cosmetic surgery.


A working model that explains how a single shift can produce seemingly opposite symptoms.

“We were surprised to find that SSRIs and other antidepressants aren’t very effective at keeping depressed patients out of hospital.”

Among the topics covered in this year's noteworthy studies: lithium and suicide prevention, mixed depression, and light therapy.

Several non-biological factors often contribute significantly to treatment resistance.

This article focuses on treatment resistance to medications in adult male and non-pregnant adult female outpatients with any type of DSM-5 diagnosed bipolar disorder.

What does the evidence tell us about digital sensors for treatment adherence in patients with schizophrenia and other psychiatric disorders?

How to decrease recidivism for individuals with serious mental illnesses who are released from jails or prisons or discharged from hospitals? Here are several effective mechanisms.

Questions and caveats about dosing remain.

Six patient types to watch for.

A novel protocol lights the way for a promising treatment for bipolar depression.

Which is more important, for whom?

Tips for having a balanced and comprehensive risk-to-benefit discussion with competent patients who want to stop their medications.

We are using 4 different approaches to bipolar diagnosis, according to the author of this commentary.

This article focuses on appropriate versus inappropriate use of antipsychotics, the importance of careful assessment, and the consequences of not treating.

Here: a Q&A about diagnostic challenges in the real world; pharmacologic and non-medication options; and management of common adverse events in patients with DSM-5 bipolar and related disorders.

A spectrum approach to diagnosis.

Not just a nuisance, no-shows are an opportunity to turn things around for patients with bipolar disorder, whose treatment adherence hovers around 60%.

A window into what your colleagues actually think and do.

Here: a plethora of treatment options, including mood-lifting stabilizers, non-antidepressants, psychotherapy, and lifestyle interventions.