Rational Off-Label Prescribing: A Review With Joseph F. Goldberg, MD, and Henry Nasrallah, MD

Joseph F. Goldberg, MD, sat down with Henry Nasrallah, MD, to discuss the essentials of off-label prescribing and uses of polypharmacy. Nasrallah highlighted his landmark analysis showing that 88% of Diagnostic and Statistical Manual (DSM) psychiatric diagnoses have no US Food and Drug Administration (FDA)-approved medication, leaving clinicians needing to prescribe off-label for many patients.^1,2