Mount Sinai Department of Psychiatry

Experts reveal why psych medication nonadherence is common, how to discuss it without blame, and tools like CAE and injectables to prevent relapse.

Experts unpack why most psychiatric care relies on off‑label meds, how neuroscience guides safe polypharmacy, and what could reshape FDA approvals.

How AI can aid everyday psychiatry—TRD prediction, suicide risk, and smartphone phenotyping—plus why data quality and workflow still block adoption.

Experts urge early bipolar disorder treatment, highlighting lithium’s underuse despite neuroprotective, antisuicidal benefits and evidence that delays worsen outcomes and responsiveness.

Experts explain how careful pediatric psychopharmacology and early intervention protect development, curb relapse, and address substance-use risk.

Expert psychiatrists share new ASCP deprescribing guidance, tackling overprescribing, primary-care challenges, and practical tapering strategies to improve safer, patient-centered mental health care.

Explore psychopharmacologic options for personality disorders in this podcast.

Explore why sexual health matters after 65 and how clinician comfort boosts disclosure.

Learn more about medication use in pregnancy and postpartum, including risks and benefit analysis.

Analysis of speech, acoustics, and facial cues reveals early psychosis and suicide risk.

Guidance on psychotropic meds in pregnancy: personalize decisions, coordinate care, and plan early to prevent postpartum relapse.

Planning for prevention of perinatal psychiatric relapse with safer medication options.

Computational phenotyping reveals prodromal psychosis clues, connects biomarkers to symptoms, and shows why stress and cannabis reduction matters.

Psychiatry leaders unpack pharmacogenetic testing hype, spotlight 4 actionable genes, and urge evidence-based use with therapeutic drug monitoring for personalized treatment.

Experts discuss rapid cycling and bipolar II, and weigh lithium as an often overlooked treatment option.

Psilocybin therapy shows fast, lasting relief for depression; clinicians discuss trial hurdles and emerging promise for PTSD and addiction in this podcast.

Learn when CBT/IPT beats medications, when to combine antidepressants, and why patient preference drives depression recovery in 6–12 weeks in this podcast.

A multicenter study tests SAINT TMS for postpartum depression.

Clinicians explore neuroscience-guided off-label prescribing.

Explore GLP-1 agonists and their "truly transformative" role in psychiatry in this podcast.

Psychiatry experts explain why off-label psych meds and polypharmacy can be essential.

Learn why patients skip psych meds and how to boost adherence with stigma-free dialogue, routine hacks, family support, and deprescribing tips.

Learn more about the treatment of depression, selective serotonin reuptake inhibitors, and pregnancy in this podcast.

A relationship between inflammatory skin disease and depression revealed in new research.

Psychiatry experts unpack why off-label medications are common and how evidence and dosing guide care.

Experts discuss why early treatment and tailored combos can curb bipolar disorder.

Experts unpack child psychiatric medication: safety, early intervention, suicide risk, and managing side effects.

New research trains cognitive control to curb stimulant cravings.

Explore the complexities of psychopharmacology in treating personality disorders, focusing on symptom management and the importance of therapeutic alliances.

Eric Nestler, MD, PhD, reflects on his research and new role as dean of the Icahn School of Medicine.