Julian Lagoy, MD

As the world slowly sheds the weight of COVID-19, there is an opportunity for psychiatrists to pause and consider the role they are about to play in the coming months and years. Never before has the entire modern world been subjected to such collective feelings of fear, uncertainty, anxiety, and sorrow—and loneliness.

Individuals around the world did their part to slow the spread of 

 by staying home. Populations that were not used to being alone, like children and teenagers, were suddenly cut off from their social networks. Family members were often isolated from each other. Many individuals have died from COVID-19, often without family, with little comfort or human contact except hospital staff.

About 36% of Americans reported feeling “serious loneliness” in the wake of the pandemic, according to 

 Of these respondents, 61% were aged 18 to 25 years, and 43% reported increases in loneliness since the pandemic began.

The effects of pandemic-related isolation have been felt in every corner of society. It may take the form of exacerbated symptoms in some patients or freshly developing signs of mental illness in others. Medically, loneliness has been linked to 

 It is also linked to increased rates of depression, anxiety, substance abuse, domestic abuse, and suicide.

Psychiatry often relies on pharmaceuticals to treat mental illness; this 

 serves as a good reminder that the best cure for loneliness can be as simple as kindness and compassion.

More than any other species, humans are dependent on others for longer periods of time. In fact, the average individual spends about 80% of their waking hours in the company of others.

 is a state of mind that is characterized by feeling unwanted, empty, and cut off from other human beings.

 It is also described as a negative reaction to the discrepancy between the relationships we desire versus those we have.

Loneliness is not necessarily the result of being alone. One can easily feel lonely even when surrounded by others. Because loneliness is more often a perception, feelings of isolation can trigger hypervigilance, in which the world appears to be a threatening place.

 Individuals who are lonely tend to be more critical of themselves.

 When these negative expectations are confirmed by the behavior of others, this creates a 

 that is accompanied by feelings of hostility, stress, pessimism, anxiety, and low self-esteem.

Loneliness apparently loves company, with studies describing it as 

 It appears to spread through friends, rather than family members, and occurs in clusters, extending up to 3 degrees of separation.

 Loneliness can be addressed both as a group and individually. One way to prevent loneliness is to encourage social activity. Obviously, for some people it is very hard to be social; this is where emphasizing resiliency and perseverance is important. 

“In loneliness, the lonely one eats himself; in a crowd, the many eat him,” Friedrich Nietzsche once said.

 Culturally, loneliness can be seen as a sign of weakness or self-pity. For instance, 1965 study of rhesus monkeys Found that when a group of socially isolated monkeys were reintroduced to their colony, they were driven off or eliminated.

In 2018, the United Kingdom’s BBC Radio 4 released results from 

, the largest survey ever conducted on the subject.

 They study included more than 55,000 participants, aged 16 to 99 years, hailing from 237 countries, islands, and territories. It found that loneliness was higher in individualistic cultures such as the United States and Western Europe, which placed high value on self-reliance, loose social networks, and chosen relationships. In contrast, cultures with strong collectivist norms, including some Asian countries, are built on interdependence, tighter social networks, and stronger family connections. Some of these countries include Brazil, India, and the Philippines.

The study found young individuals experienced the most loneliness, with 40% of 16- to 24-year-olds feeling lonely often or very often, in comparison with 29% of individuals aged 65 to 75. Young men in particular were more susceptible to feelings of loneliness, and their loneliness was more intense and longer-lasting.

Most of the research on loneliness was conducted before COVID-19 sent us into lockdown, so it is too soon to consider the pandemic’s long-term effects. However, recent studies have tracked the impact of social distancing and quarantine, and they have left an intriguing bread-crumb trail of predictions.

When COVID-19 struck, many experts worried suicide rates would skyrocket.

 A 2020 report from the Centers for Disease Control and Prevention showed a 35% increase in suicide mortality in the US from 1999 to 2018, a trend most people expected to continue.

A March 2020 rapid review disseminated 24 studies

 in 10 countries that examined the psychological impact of quarantine.

 It included those affected by SARS, Ebola, H1N1 influenza, Middle East respiratory syndrome, and equine influenza. Common quarantine side effects included posttraumatic stress disorder (PTSD), confusion, and anger. Stressors included the extension of quarantines, fear of infection, frustration, boredom, inadequate supplies and information, financial loss, and stigma.

The review also found health care workers in particular suffered from the loneliness and isolation of quarantine. Theyendured increased severe symptoms of 

, felt stigmatized, and reported greater loss of income. Health care workers also reported feeling lonely, guilty, angry, helpless, isolated, nervous, and sad. Many linked their quarantine experience to alcohol abuse and dependency symptoms. They also engaged in avoidance behavior, often not showing up to work or avoiding direct interactions with patients.

Like every facet of society, health and mental health organizations have had to rethink how to serve their patients, especially when they could not be treated in person. Mental health care providers were encouraged to find alternate ways to deliver services, provide clear pathways for those considering suicide, and quickly offer bereavement services when needed. We can assess for loneliness by using the revised University of California, Los Angeles (UCLA) loneliness scale.

 One way to approach the conversation is to ask patients what they are doing during their free time and if they have any friends or family they spend time with. Since the COVID-19 pandemic, it is likely a lot more patients have indicated they are lonely.

 examined the relationship between 30,000 patients and their therapists.

 In a review of 295 independent studies published between 1978 and 2017, it found that positive clinical outcomes correlated with the strength of the therapeutic alliance between patients and their therapists. The better the relationship, the better the prognosis. The therapeutic alliance has become even more important due to the pandemic and quarantine. As psychiatrists, we must strengthen our relationship with patients so they trust us and improve. This is just as important and essential as medication management.

Individuals need quality information and strategies to cope with loneliness, in addition to help identifying and managing self-defeating thoughts. Comprehensive assessments like the revised UCLA Loneliness Scale and access to round-the-clock counseling networks could throw vital lifelines to patients suffering from loneliness.

In France, the VigilanS suicide prevention system was implemented before COVID-19 began. It rapidly adapted by following up with at-risk patients on the 10th day rather than the 20th. Early data regarding this intervention shows a sharp decrease in 

 by those involved, however this is an ongoing study and final results are not yet published.

 France’s art community also jumped to provide support. Cov’ Art is a public art movement designed to shore up resilience and provide messaging about suicide and interindividual violence. Some programs in the US include the National Alliance on Mental Illness, the National Suicide Prevention Lifeline, and the American Foundation for Suicide Prevention.

, smartphones, and videoconferencing have also played a huge role in maintaining connections. Prior to COVID-19, social media was seen as something that made many individuals feel lonely.

 During the pandemic, however, social media was one of the few safe ways to stay in contact with other people. In one study, it was noted that while adolescents indicated increased social media use during lockdown, it was not associated with increased happiness. It even showed a negative correlation between using social media and happiness. It also noted that using social media as a substitute for physical social relations makes adolescents feel less happy.

More than anything, individuals need to be comforted that they are not alone and shown a way to overcome their loneliness. Often, the solution is to address loneliness with kindness. 

 observed 2 groups for 6 weeks; 1 that performed acts of kindness for themselves and 1 that conducted good deeds for others.

 The group that behaved altruistically flourished psychologically through improved social relationships and feelings of greater joy and wellbeing.

 suggested that how we treat loneliness is a bellwether of not only society’s emotional and physical health but also its moral health.

 In a society where many prioritize themselves, we need to help our patients—and ourselves—commit to being both present and compassionate for each other.

Ironically, suicide rates generally dip after major events that are shared by large populations.

 During COVID-19, CDC statistics found provisional 

 Provisional suicide mortality rate estimates provide an early indication of shifts in suicide mortality trends.

 After the 9/11 terrorist attacks, suicide rates in New York declined significantly during the 180 days after the event.

 Researchers suggest that a “pulling together” effect may be the reason behind this phenomenon. Shared experiences during COVID-19 led to a powerful sense of togetherness that helped to keep suicidal thoughts in check. 

 suggested that the “need to belong is so powerful that, when satisfied, it can prevent suicide.”

 It noticed that fewer suicides occurred on Super Bowl Sundays, likely due to an increase of shared membership and group interaction on those days.

It is this line of reasoning that developed the 

 First, suicide ideation occurs as a reaction to feelings of psychological pain and hopelessness. Second, feelings of connectedness were a key protective factor against escalating ideation. Third, suicide follows ideation when a someone determines they have the disposition and practical capacities to carry out the event.

To be sure, the stress of COVID-19 has affected mental health around the world. 

 reported that more than 40% of respondents had symptoms of anxiety or depression.

 It is interesting that while suicide rates declined, depression rates have increased. Major events that affect a whole population have an interesting effect in decreasing suicide while increasing rates of depression. Additionally, 26% indicated that they had started or increased substance use as a way to cope.

As psychiatrists, we tend to be biased in thinking that everything can be fixed with medication; however, the danger is that we forget to see the human person in front of us. While medication can help, often their problem is much more complex and needs more than medication treatment. We should not overlook patients we think are lonely and instead provide tips, such as being active on social media and staying in touch with friends through Zoom and Facebook. Although in-person relationships are always better than virtual ones, virtual ones are better than nothing. The worst thing to do when lonely is to completely isolate and not talk to anyone through social media. 

As psychiatrists, we are on the front lines and can affect whether some people live or die. Let us rise to the occasion and treat everyone with kindness and compassion and in doing so, save thousands of lives.

is staff psychiatrist at Community Psychiatry in San Jose, CA.

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https://mcc.gse.harvard.edu/reports/loneliness-in-america

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The pandemic has kept people apart. What are the mental health consequences of being alone? And what would be the benefits of getting back together? 

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, talks about National Depression Education and Awareness Month and National Depression Screening Day, October 8.

He briefly explains the epidemiology and impact of depression both worldwide and in the United States and describes how he screens for and treat depression. Also discussed are common screening tools such as the PHQ-9 and Beck Depression Inventory.

Dr Lagoy speaks to the prevalence and probability of treatment-resistant depression and the different options for treatment. He describes the process of switching a medication versus his rationale for adding an adjunctive medication. Lastly, he briefly mentions other alternative non-medication treatments for depression if medications fail.

Videos

Prepare for National Depression Education and Awareness Month with a discussion on initiatives and treatments. 

Julian Lagoy, MD

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