Depression

What to do once treatment-resistant depression is established based on risk factors and exclusion of other conditions? Insights here-and a treatment algorithm.

The discovery that a single IV infusion of low-dose (subanesthetic) ketamine exerts rapid antidepressant effects constitutes an expansion in our understanding of the neurobiology of depression and provides new avenues for drug development.

Chronobiology-the science of daily (circadian), monthly, tidal, and seasonal rhythms-has undergone exponential growth in the past decade, with major discoveries at the molecular and neuroanatomic level.

The “story behind the story” is not the over-prescription of antidepressants-though it happens-but the under-availability of optimal treatment.

Imagine an end to psychiatric episodes that threaten job and family, no more hospitalizations, and a chance for a long life not cut short by mental illness and its complications. What can we take away from the HIV/AIDS story for the treatment of mental illness?

A brief review of interesting new findings on suicidality and depression treatment in youths.

Given the greater frequency of depression than manic episodes in bipolar disorder, what clues indicate bipolar disorder rather than unipolar depression?

An update on the diagnosis, causation, and treatment of chronic depressive problems. The focus is on the recently introduced diagnostic category of persistent depressive disorder.

Here: the history of psychotic depression for the Study of the Pharmacotherapy of Psychotic Depression (STOP-PD), a summary its epidemiology, significance, diagnostic complexity, and treatment, as well as case vignettes.

This article reviews the most recent (after 2010) published guidelines on bipolar depression.

With over 2 dozen FDA-approved antidepressants on the market, it is reasonable to ask: which antidepressants are most effective?

Evidence has accumulated on the efficacy of transcranial direct current stimulation in major depression. The authors review its potential mechanism of action, findings from recent clinical trials, and potential role in the treatment of depressive disorders.

The removal of the so-called “bereavement exclusion” (BE) from DSM-5 was one of the most difficult and controversial decisions the DSM-5 work groups made, and many clinicians continue to find the distinction between ordinary grief and major depression confusing.

Many patients report that smoking helps them with their stress and psychological disturbances. However, smoking may actually worsen some of these symptoms. When is the right time for your patients to quit?

There has been a lot of publicity about hearing loss as a predisposing factor to depression and dementia. What about visual problems? These questions and more in this expert Q&A.

In this podcast, B. Andrew Farah, MD, looks at shortcomings of current therapy that make treatment-resistant depression so common, offers insights into the genetic underpinnings of TRD, and focuses on a new treatment paradigm.

What happens when our patients get pregnant or plan to get pregnant? What if psychiatric illness manifests during pregnancy or the perinatal period? Dr Elizabeth Fitelson answers these questions and more in this video.

Vitamin D has been hailed as the “sunshine” vitamin with many therapeutic attributes. The authors explore the association between vitamin D deficiency and increased risk of depression.

When Wordsworth rhapsodized about yellow flowers, it is doubtful that he expected his verse to translate into the mental health realm. Yet that is exactly what happened.

When a full-time writer's husband was diagnosed with cancer, she found writing poetry helped her cope. She guessed that others would, like her, find their experiences with cancer best expressed through poetry. So began The Cancer Poetry Project.

What do we know about eating disorders and what are the next steps in treatments and research? More in this podcast.

Psychiatrists have found ways to bring their expert skills and knowledge to the care of medically ill patients who are nearing the final phase of life.

Because half of pregnancies in this country are unplanned, it's crucial to counsel women of reproductive potential about their medications-regardless of their plans to conceive.

With the multitude of nutritional products available to patients via the Internet and health-food stores, psychiatrists need to be prepared to respond to questions from patients about the value of these supplements.

Starting in 2015, psychiatrists will have to juggle antidepressant selections for Medicare patients. What might this mean for your patients?