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Here are highlights from this week in Psychiatric Times, including FDA approvals and conference coverage.

Here's how best to manage polypharmacy in patients with traumatic brain injury.

How often do you revisit a comprehensive medication reconciliation?

Facing limited resources, cultural barriers, and complex mental health cases, A newly qualified doctor’s year in rural South Africa offers a deep dive into psychiatry in underserved areas.

Check out the top 5 best practice recommendations for treating children and adolescents with psychotropic and combination therapies.

Here are highlights from this week in Psychiatric Times, including FDA approvals and trial updates.

What is the appropriate duration for antipsychotic use and how can you safely taper or discontinue them?

How can we optimize and expand our knowledge of neuroplasticity?

Learn more about Alto Neuroscience's ALTO-300, in ongoing phase 2b trials as an adjunct treatment for major depressive disorder.

With MM120 in phase 3 in the MindMed trial, what place do psychedelics hold in psychiatry?

An observational cohort study found patients at less risk of hospitalization for alcohol use disorder when also being treated with a GLP-1 agonist anti-diabetic/obesity agent.

In this CME article, learn more about recent developments with lithium as they relate to renal issues.

Data presented at ACNP meeting demonstrated safety, tolerability, and efficacy for SPN-820 for MDD.

A poster at the ACNP Annual Meeting utilized a novel risk-informed case-control design to improve biomarker differentiation for ADHD.

Check out 2 new psychopharmacology innovations!

Stephanie Gorka, PhD, shared findings at the ACNP Annual Meeting on orexin receptor agonists addressing AUDs.

Previewing the 63rd ACNP Annual Meeting, which is set to highlight the latest research in psychiatry.

In a new study, researchers found the subtype of childhood trauma impacts the effectiveness of antipsychotic medications.

Calling it a barrier to care, FDA committees decide to end clozapine REMS.

There is an accumulating body of evidence that metformin may have benefits in aging beyond its effect on glycemic control.

This article explains the role of medications that have high affinity to block dopamine D4.

New positive results demonstrate the efficacy and safety of lumateperone (Caplyta) 42 mg for the prevention of relapse in adult patients with schizophrenia.

Learn more about a specific subset of mood disorders.

What’s the truth about benzodiazepines?

Although safety and tolerability was positive, ALTO-100 failed to reach primary endpoint in MDD study.