Opinion|Videos|December 1, 2025
A New Option: Getting TDM Data Faster
Author(s)Jonathan M. Meyer, MD, DLFAPA
Exploring how rapid testing technologies can change clinical practice and challenge assumptions about the “gold standard.”
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This video covers the following questions:
- Historically, LCMS has been considered the gold standard for clozapine level measurement. Can you help us understand why that is—and what limitations come with it in real-world psychiatry?
- There’s often discussion about the metabolite-to-parent ratio (MR ratio) in clozapine monitoring. How does rapid testing change the need or relevance of relying on MR ratios?
- How might rapid TDM help bridge gaps in care for patients seen in community settings or those with limited lab access?
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