Schizophrenia/Psychosis

In this CME article, familiarize yourself with various pharmacokinetic, pharmacodynamic, and patient-specific factors to review to develop a successful cross-titration plan from one antipsychotic to another.

A new meta-analysis identifies target for improved care in patients with schizophrenia.

Thinking about sex and sleep in schizophrenia: Researchers performed a large cross-sectional study of sex differences in insomnia and cognition in chronic schizophrenia.

Have you had difficulty with differential diagnosis when patients have manic symptoms and psychosis? One doctor discusses the related DSM-5 criteria changes and some of their implications for psychopharmacology.

The glass is half full: reflections on where we are and hope for where we are heading in psychiatry.

The supplemental new drug application of brexpiprazole for the treatment of schizophrenia in pediatric patients aged 13 to 17 received FDA approval.

Is cannabis’ effect on schizophrenia being downplayed?

What treatment strategies are available to improve the quality of life for older adults who are aging with schizophrenia?

Should we go up? Researchers performed a dose-response meta-analysis of randomized controlled trials in acute phase schizophrenia.

Does clozapine increase the risk of severe COVID-19 infection? Researchers performed a larger register-based cohort study of this association.

Negative symptoms of schizophrenia are associated with higher overall morbidity and decreased functioning. These study results offer hope.

How does schizophrenia as a pathology differ from normal human experience?

Put out your cigarette. Researchers performed a cohort study of the impact of cigarette smoking on life expectancy in schizophrenia, schizoaffective disorder, and bipolar disorder.

Comorbidity or medication adverse effect? Researchers performed a nested case-control study of new-onset obsessive-compulsive disorder following antipsychotic use in schizophrenia.

Unintentional overdose with antipsychotics plus opioids. Researchers performed a population-based cohort study of the risk of overdose associated with co-prescription of antipsychotics and opioids.

All in a good night’s sleep? Researchers performed a pharmacovigilance study of second-generation antipsychotics and mood stabilizers as the suspected agent of psychiatric adverse drug reactions (insomnia and suicide/ideation/behavior/death).

Syllable and sound are still the primary means for taking the measure of thoughts and emotions, the building blocks and foundations of psychiatric work.

At the Annual Psychiatric Times World CME Conference, an all-star lineup of presenters will share their latest research. Check out this preview of the full agenda.

Mental illnesses are too often shrouded in secrecy and shame. What would happen if we spoke out about the cases we knew best—the ones in our own families?

Secondary causes for psychosis are more common in older adults (65 years or older) than in younger patients. Here are 6 possible culprits.

The one-of-its-kind 6-month paliperidone palmitate treatment for schizophrenia has received FDA approval.

What can philosophy learn from madness?

The emergency department is a primary care location for patients with schizophrenia. Here’s how to manage schizophrenia in this particular setting in an informed and caring manner.

Most psychotic disorders appear in adolescents or young adults, but some also occur during later life. Here's how to recognize and treat them.

Artificial intelligence and natural language processing provide powerful new tools to measure thought disorder and negative symptoms in schizophrenia.

How is “disease” defined? A popular criticism of psychiatry gets debunked.

A growing body of scientific literature makes the case.

An extended release, ultra-long acting antipsychotic takes another step forward in the approval process.