Schizophrenia/Psychosis

What is the appropriate duration for antipsychotic use and how can you safely taper or discontinue them?

Check out the positive topline results from a phase 2 dose finding trial evaluating N-methyl amisulpride (LB-102) in adult patients with acute schizophrenia.

Perhaps, in our modern arguments over the reality of mental illness, we are merely reinventing the wheel—or maybe, just spinning our wheels.

An FDA committee recently decided the clozapine REMS protocol was no longer necessary. How will this impact clinicians?

A recent longitudinal, retrospective study aimed to examine antipsychotic prescribing and rehospitalization rates in a forensic psychiatric sample.

Researchers investigated the link between psychosis, criminal sanctions, and mortality rates following discharge from a hospital for acute psychosis.

Negative symptoms pose significant challenges for individuals with schizophrenia and their caregivers.

Psychiatry: one of the most dynamic and rapidly evolving specialties in medicine.

New research links reduced synaptic density,early psychosis, and cannabis use, offering insights into negative symptoms and potential interventions.

The presentation of catatonia can vary, making its management challenging, particularly in resource-limited settings in South Africa.

Let's look back on a year marked by advancements and ongoing challenges in psychiatry.

Learn more about best practices when treating comorbid trauma and psychosis.

In a new study, researchers found the subtype of childhood trauma impacts the effectiveness of antipsychotic medications.

What does the clozapine REMS recommendations from the FDA Advisory Committees mean for clinical care?

Gordon Lavigne, MEd, CEO of the Schizophrenia & Psychosis Action Alliance, talk about the joint FDA committee's vote on clozapine REMS.

Calling it a barrier to care, FDA committees decide to end clozapine REMS.

How is the study of muscarinic receptors transforming schizophrenia treatment?

How can you best discuss long-acting injectable options with your patients living with schizophrenia?

Traumatic life events are common among individuals who experience psychosis. Here's how best to assess and treat.

Emraclidine once-daily, oral monotherapy treatment for adults with schizophrenia experiencing acute psychotic symptoms, failed to meet the primary endpoints in the 2 phase 2 EMPOWER trials.

The medication treatment of schizophrenia has finally diversified to a novel neurotransmitter system: the muscarinic cholinergic system.

New positive results demonstrate the efficacy and safety of lumateperone (Caplyta) 42 mg for the prevention of relapse in adult patients with schizophrenia.

A new collaboration to address sleep disturbances associated with cognitive impairment, an unmet need.

Posters from Psych Congress confirm the durability of long-term treatment with xanomeline/trospium (Cobenfy).

Here's what you need to know about the latest FDA-approved schizophrenia treatment.