Schizophrenia/Psychosis

There is evidence for overlapping risk factors and symptomatology between ADHD and psychotic disorders. New research investigates the association between ADHD during childhood and the subsequent risk of developing a psychotic disorder.

Ronald W Pies, MD, considers the evidence from pathology textbooks—and answers the critics.

A lawyer discusses how the legal system treats (and mistreats) those with mental illnesses.

A new risperidone capsule for the treatment of schizophrenia sees positive phase 2 study results.

Patient perspectives in academic discourse in psychiatry have historically been a neglected area. What are some of the consequences and implications of this absence? How has this affected both psychiatry and those who have been excluded? These questions and more are discussed.

While this digital therapy failed to meet its primary endpoint in a recent clinical trial, results suggest it may improve paranoia in general.

A quick primer on nomenclature, issues to consider, and switching.

CRL cites lack of substantial evidence of efficacy needed for approval.

When do cognitive impairments emerge in patients with schizophrenia?

The war experiences of physicians and scientists shaped their research agendas.

A DSM-5 diagnosis requires a biopsychosocial case formulation—not just a symptom checklist.

Aerobic exercise has been found to exert a positive effect on global cognition and some, but not all, cognitive domains in patients with schizophrenia.

What is the long-term, real-world effectiveness of pharmacotherapies for schizoaffective disorder? An investigation into 2 nationwide cohorts of patients living with schizophrenia provides new details.

An antipsychotic changed the life of not only 1 man, but an entire family.

Does switching antipsychotics quell weight gain in patients with severe mental illness? A meta-analysis of 59 relevant studies provides insights.

About 2.4 million people in the US experience dementia related psychosis, yet only half ever receive a diagnosis.

A synthesis of quantitative reviews on the relationship between cannabis use and psychosis.

Data published in The New England Journal of Medicine shows promise for a novel schizophrenia treatment.

The chief medical officer of Karuna shares his thoughts exclusively with Psychiatric Times.

Millions of Americans will suffer brain injuries this year, and many of them will need a psychiatrist’s help.

Is this phase 2 trial the end of the road for a potential new treatment?

Is it possible to use cognitive testing, which is brief, easily performed, reliable, and noninvasive, to identify individuals at risk for psychosis?

How do men versus women with schizophrenia fare clinically, functionally, and neuropsychologically over the long term?

Selfhood: a complex and continuously evolving identity that is anchored in the patient's history and dependent on language and memory. But there is so much more.

Although the clinical symptoms of psychotic disorders are dramatic and are what most clinicians focus on as their treatment targets, impairments in a wide range of cognitive function are observed in these illnesses.