Articles by Lisa Harding, MD

A patient's improving score does not always translate into a patient who feels better, and Erin Crown explains how anhedonia and cognitive symptoms account for the gap.

More than half of patients treated for depression don't believe full remission is achievable. The panel explores what success should mean to the patient in front of you, and why patients rarely admit they've stopped taking a medication.

Standardized questionnaires matter, but Erin Crown leans on detailed conversation about a patient's daily routines to catch functional changes that no scale fully captures.

Standardized rating scales define response and remission in clinical trials, but Erin Crown argues real recovery means returning fully to the life a patient had before depression began.

A PHQ-9 score can mislead as easily as it clarifies. The panel unpacks the gap between rating-scale remission and how patients actually experience recovery, using real cases where appearances and scores diverged sharply.

Precision medicine looks different in psychiatry than in oncology. The panel discusses why personalizing MDD care starts with a complete patient history, and how clinical experience, evidence, and patient goals combine to guide treatment.

Explore how clinicians weigh ECT, TMS, ketamine, and vagus nerve stimulation for treatment-resistant depression—balancing speed, access, durability, and patient preference.

An esketamine expert reflects on 7 years of nasal spray use and asks why racemic ketamine faces none of the same rules.

Many symptoms that most impair patients with major depressive disorder go unspoken until treatment starts working, making early recognition and patient-defined goals central to effective care.

Depression's cardinal symptoms are often invisible to the patient reporting them. Dr. Harding and Dr. Citrome examine why diagnosis, not treatment, remains psychiatry's hardest task, and how family observation and screening for bipolar depression change the diagnostic path.

An expert expresses concerns over NRx-100's "expanded access" for ketamine, questioning its safety claims and prioritizing market strategy over patient care.

Here's how embracing a comprehensive, patient-centered approach and staying informed about emerging treatments can help mental health professionals make a difference in the lives of patients with TRD.

Don't miss this session at the APA 2023 Annual Meeting in San Francisco!

Integrated Care and Treatment-Resistant Depression
BySteven P. Levine, MD,Angelos Halaris, MD, PhD, APA, ACNP, CINP,Lisa Harding, MD,Patricia Ares-Romero, MD, FASAM Custom ViewPoints Video Program

Electroconvulsive Therapy for Depression
BySteven P. Levine, MD,Angelos Halaris, MD, PhD, APA, ACNP, CINP,Lisa Harding, MD,Patricia Ares-Romero, MD, FASAM Custom ViewPoints Video Program

Traditional Classes of Antidepressant Therapies
BySteven P. Levine, MD,Angelos Halaris, MD, PhD, APA, ACNP, CINP,Lisa Harding, MD,Patricia Ares-Romero, MD, FASAM Custom ViewPoints Video Program

Frontline Psychotherapy for Depression
BySteven P. Levine, MD,Angelos Halaris, MD, PhD, APA, ACNP, CINP,Lisa Harding, MD,Patricia Ares-Romero, MD, FASAM Custom ViewPoints Video Program

Treatment-Resistant Depression: Financial Support for Esketamine Therapy
BySteven P. Levine, MD,Angelos Halaris, MD, PhD, APA, ACNP, CINP,Lisa Harding, MD,Patricia Ares-Romero, MD, FASAM Custom ViewPoints Video Program

Incorporating Esketamine into Practice for Treatment-Resistant Depression
BySteven P. Levine, MD,Angelos Halaris, MD, PhD, APA, ACNP, CINP,Lisa Harding, MD,Patricia Ares-Romero, MD, FASAM Custom ViewPoints Video Program

Getting Certified to Administer Esketamine for Treatment-Resistant Depression
BySteven P. Levine, MD,Angelos Halaris, MD, PhD, APA, ACNP, CINP,Lisa Harding, MD,Patricia Ares-Romero, MD, FASAM Custom ViewPoints Video Program

Treatment-Resistant Depression: Administering Esketamine to Patients
BySteven P. Levine, MD,Angelos Halaris, MD, PhD, APA, ACNP, CINP,Lisa Harding, MD,Patricia Ares-Romero, MD, FASAM Custom ViewPoints Video Program

REMS Safety Program for Esketamine in Treatment-Resistant Depression
BySteven P. Levine, MD,Angelos Halaris, MD, PhD, APA, ACNP, CINP,Lisa Harding, MD,Patricia Ares-Romero, MD, FASAM Custom ViewPoints Video Program

Response to Esketamine Therapy for Treatment-Resistant Depression
BySteven P. Levine, MD,Angelos Halaris, MD, PhD, APA, ACNP, CINP,Lisa Harding, MD,Patricia Ares-Romero, MD, FASAM Custom ViewPoints Video Program

Monitoring Patients on Esketamine Therapy for Treatment-Resistant Depression
BySteven P. Levine, MD,Angelos Halaris, MD, PhD, APA, ACNP, CINP,Lisa Harding, MD,Patricia Ares-Romero, MD, FASAM Custom ViewPoints Video Program

Esketamine for Treatment-Resistant Depression: Patient Selection Criteria
BySteven P. Levine, MD,Angelos Halaris, MD, PhD, APA, ACNP, CINP,Lisa Harding, MD,Patricia Ares-Romero, MD, FASAM Custom ViewPoints Video Program

Intranasal Esketamine for Treatment-Resistant Depression
BySteven P. Levine, MD,Angelos Halaris, MD, PhD, APA, ACNP, CINP,Lisa Harding, MD,Patricia Ares-Romero, MD, FASAM Custom ViewPoints Video Program

Current Guidelines for Managing Treatment-Resistant Depression
BySteven P. Levine, MD,Angelos Halaris, MD, PhD, APA, ACNP, CINP,Lisa Harding, MD,Patricia Ares-Romero, MD, FASAM Custom ViewPoints Video Program

IV Ketamine for Treatment-Resistant Depression
BySteven P. Levine, MD,Angelos Halaris, MD, PhD, APA, ACNP, CINP,Lisa Harding, MD,Patricia Ares-Romero, MD, FASAM Custom ViewPoints Video Program

Prevalence of Treatment-Resistant Depression
BySteven P. Levine, MD,Angelos Halaris, MD, PhD, APA, ACNP, CINP,Lisa Harding, MD,Patricia Ares-Romero, MD, FASAM Custom ViewPoints Video Program