Major Depressive Disorder

What is the association between the gut microbiome and response to SSRIs in patients with depression?

Greg Mattingly, MD, and Jeremey Schreiber, MSN, PMHNP-BC, discuss best practices for monitoring and follow-up with patients with major depressive disorder (MDD) to ensure treatment efficacy and safety.

Practitioners discuss their approach to treatment with their patients with major depressive disorder (MDD).

Experts discuss how practitioners are viewing major depressive disorder (MDD) as a chronic condition vs an episodic condition.

Greg Mattingly, MD, and Jeremey Schreiber, MSN, PMHNP-BC, discuss navigating the challenge of a “one size fits all approach” when treating and identifying the specific needs of patients with major depressive disorder (MDD).

Practitioners discuss the rates of undertreatment in patients suffering from major depressive disorder (MDD).

Greg Mattingly, MD, and Jeremey Schreiber, MSN, PMHNP-BC, comment on the perception of major depressive disorder (MDD) within the healthcare community and the clinical and practical implications of is this condition.

Fatigue: a very common physical complaint that often accompanies depressive disorders.

From obesity and metabolism in first-episode MDD to psychiatrist liability and suicide, here are highlights from the week in Psychiatric Times.

Metabolic mediators of anxious depression? Researchers investigated metabolic correlates of overweight/obesity in patients with MDD.

Looking to stay up to date on MDD research? This research collection reviews outcomes on metabolic abnormalities, biomarkers, and more.

Presenters at the 2023 APA Annual Meeting compared definitions of treatment-resistant depression.

Check out this review of the 2023 APA Annual Meeting presentation on the efficacy and safety of repeat treatment courses using novel medicine, zuranolone.

An inside look at what treatments are being discussed in San Francisco...

Study results presented at the 2023 American Psychiatric Association Annual Meeting.

Don't miss this session at the APA 2023 Annual Meeting in San Francisco!

Test your knowledge on issues in major depressive disorder.

First of its kind culturally sensitive adherence scale factors in CVD risk factors to find ways to best support patients.

“Our hope for patients suffering from TRD is that their serious, but often treatable condition is recognized earlier in the treatment paradigm, and they are put on a treatment that works best for their specific type of depression.”

What is the current role of lithium?

From gut microbiota and SSRIs in MDD to nonpharmacological interventions following TBI, here are highlights from the week in Psychiatric Times.

A gut feeling? Researchers analyzed the gut microbiome in major depression disorder and its modulation by SSRI antidepressants.

New results for a study evaluating lumateperone.

Study results show that the therapy activates serotonin (5-HT) and improves stress-coping ability.

The Future of Mental Health: Ketamine Therapy Report revealed that 55% of Americans who tried at home ketamine took more than the recommended dose.

Transcranial direct current stimulation for depression.

Sleep and suicide: researchers performed a systematic review and meta-analysis of objective sleep markers of suicidal behaviors in patients with psychiatric disorders.

Researchers analyzed data from the National Survey of Religious Leaders on the state of the psychiatrist-clergy alliance.

Here are 9 things you need to know about the clinical management of major depressive disorder.

Fatigue is a very common physical complaint. What therapeutic options are available?