Major Depressive Disorder

Does a computational approach to the mind pave the way for practicing a biopsychosocial psychiatry?

How can a greater emphasis on valued experiences both promote well-being and alleviate stress in patients?

The American Foundation for Suicide Prevention collaborates with Most Days, a mental health app, to provide suicide prevention expertise and content. Learn more about the partnership here.

Axsome Therapeutics announced the robust antidepressant efficacy demonstrated in this latest study.

Home environments have a clear impact on depression treatment outcomes.

In this CME, review novel, currently available, and promising pharmacological treatment options for treatment-resistant depression.

Zuranolone, a drug for the treatment of major depressive disorder and postpartum disorder, is on a rolling submission of a new drug application.

Sidney Zisook, MD, lists these as the top 8 issues in MDD.

In this CME, evaluate the treatment options for depression among older adults.

Study supports evidence for long-term impairment in memory, executive function.

Individuals with depression may be at a greater risk to develop late-onset Alzheimer disease, but a new study suggests depression onset may help predict Alzheimer disease.

In this CME article, learn about the best ways to assess depression in the geriatric population.

Results are clinically significant for the treatment of patients with major depressive disorder.

Are lower vitamin D levels in women related to depressive mood?

Investigators have launched a 3-year study to develop predictive models that will help identify better treatment plans for patients with depression.

If approved, this will be the fourth indication for the drug, joining its approvals for episodes associated with bipolar I disorder and schizophrenia.

A new study showed zuranolone treatment in patients with major depressive disorder demonstrates a rapid and statistically significant reduction in depressive symptoms.

Study also suggests link between postpartum depression and insomnia.

Data from a clinical program evaluating the efficacy and safety of zuranolone was presented at the American College of Neuropsychopharmacology Congress. What new developments did they share?

Research also shows increased prevalence of social risks and unmet social needs.

Results suggest that psilocybin therapy may prove to be helpful in improving quality of life for patients with cancer.

New Drug Application to be submitted for MDD in late 2022, with separate filing for PPD planned for early 2023. 

Sheldon Preskorn, MD, shares insights into drug mechanisms and delivery to better help patients with major depressive disorder.

Bringing science to the practice of psychiatry has been the personal goal of Sheldon H. Preskorn, MD—the Educator of the Year.

At the Annual Psychiatric Times World CME Conference, an all-star lineup of presenters will share their latest research. Check out this preview of the full agenda.

After a string of disappointing results, mirtazapine gets another look in a recent study.

How can clinicians distinguish between ordinary grief, depression, and prolonged grief disorder?

What are the risk factors for and prevalence overweight and obesity in patients with first-episode drug-naïve major depressive disorder?

Could the emerging field of epigenetics hold the key to catching postpartum depression before it happens?