SPOTLIGHT -
Treating Depression to Prevent Dementia
According to new research, treating depression in older adults could decrease risk of dementia by 51%.
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Omega-3 Fatty Acids for Depression With Inflammation
“Fishing” for novel approaches to depression: Researchers performed randomized dose-finding trial of omega-3 fatty acids for depression with inflammation.
The Online, At-Home Ketamine Experience: A Clinician’s Dilemma
At-home ketamine treatment initiated by an online provider presents many legal, clinical, and ethical challenges...
The Week in Review: September 26-30
From older age bipolar disorder to the relationship between antidepressants and emotional numbing, here are highlights from the week in Psychiatric Times.
Antidepressants Do Not Work by Numbing Emotions
As patients improve with antidepressant treatment, emotional numbing decreases.
Dextromethorphan-Bupropion in Depression
A new—cough, cough—combination treatment for depression. Researchers performed an RCT of dextromethorphan-bupropion in major depressive disorder.
The Week in Review: September 19-23
From historic USPSTF draft screening recommendations to the need for novel treatments for bipolar depression, here are highlights from the week in Psychiatric Times.
The Need for Novel Treatments for Bipolar Depression
In this CME article, learn more about the rationale for considering novel treatments for patients with bipolar depression.
From the Pages of Psychiatric Times: August 2022
The experts weighed in on a wide variety of psychiatric issues for the August 2022 issue of Psychiatric Times.
Dosing Adjunctive Aripiprazole for Treatment-Refractory Depression
What is the optimal dose of aripiprazole as augmentation for treatment-refractory depression? Researchers performed a systematic review and dose-effect meta-analysis.
Exploring Diagnostic Strategies in the Assessment of Mixed Affective States
In this CME article, examine how current DSM nosology defines the proper method of assessing a mixed-episode patient and which diagnostic labels to give them based on their presenting symptomatology.
Novel Oral NMDA Receptor Antagonist Approved for Treatment of MDD
Dextromethorphan HBr -bupropion HCl extended-release tablets for the treatment of major depressive disorder just became FDA approved.
The Importance of Managing Psychiatric Disorders During Pregnancy and Postpartum
Treating women of reproductive age who have depression can be difficult. Here’s an overview on the subject from the 2022 Annual Psychiatric Times™ World CME Conference.
Delineating Between Depression and Grief: Key to Treatment
Is it prolonged grief or MDD? Expert shares insights at premiere annual meeting.
Update on Depression Treatments for Youth
Further evidence-based antidepressant treatments are needed for children and adolescents with depression.
The Serotonin Fixation: Much Ado About Nothing New
The SSRIs’ mechanism of action is no index of safety and efficacy.
New Review Calls Antidepressants Into Question—But Does the Review Have Merit?
A new review shows that there is no convincing evidence that depression is caused low levels of serotonin.
8 Key Issues in the World of Major Depressive Disorder
What are the biggest challenges facing both clinicians and patients, and how can we address them?
The Major Issues in Major Depressive Disorder
A psychiatrist lists the top 8 most pressing issues in MDD, from training to accessibility.
Metformin in Treatment-Resistant Bipolar Depression
Adjunctive metformin in bipolar disorder. Researchers performed a randomized clinical trial of treating insulin resistance to improve clinical outcomes in treatment-resistant bipolar depression.
Positive Results From SKYLARK for Patients With Postpartum Depression
Zuranolone, an investigational oral drug being evaluated in women with postpartum depression, sees positive phase 3 study results.
Positive Results for Dextromethorphan-Bupropion ASCEND Phase 2 Clinical Trial
Axsome Therapeutics announced the robust antidepressant efficacy demonstrated in this latest study.
Mind-Body Resilience for Women: A Focus on Depression
Here’s why we should be paying special attention to women's depression treatment.
Study Examines Best Practices for Managing Perinatal Depression
Recommendations are often vague, contradictory, according to investigators.
The Effect of Socioeconomic Factors on Depression Treatment
Home environments have a clear impact on depression treatment outcomes.
Promising Strategies for Treatment-Resistant Depression
In this CME, review novel, currently available, and promising pharmacological treatment options for treatment-resistant depression.
Rolling NDA Submission of Zuranolone for Treatment of Major Depressive Disorder
Zuranolone, a drug for the treatment of major depressive disorder and postpartum disorder, is on a rolling submission of a new drug application.
From the Pages of Psychiatric Times: April 2022
The experts weighed in on a wide variety of psychiatric issues for the April 2022 issue of Psychiatric Times.
Individuals Cite Exercise, Gaming as Top Ways to Address Mental Health Issues
The most common issues during the COVID-19 pandemic included stress, anxiety.
Top 8 Issues in Major Depressive Disorder
Sidney Zisook, MD, lists these as the top 8 issues in MDD.