Major Depressive Disorder

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What are the psychological and physiological effects of persistent loneliness? How prevalent in the US? What role can cognitive behavioral therapy play for persistently lonely people? In this podcast, an expert offers a brief overview of this underappreciated, but often overlooked, problem.

Depression is a frequent psychiatric comorbidity among patients with restless leg syndrome. The case presented here illustrates the importance of evaluating for RLS symptoms in patients with major depressive disorder who complain of insomnia.

Mood switching is not uncommon and it is much more prevalent in depressed juveniles than in depressed adults, and there is a large apparent excess of antidepressant-associated switching over reported spontaneous diagnostic changes to bipolar disorder. Details here.