Special Reports

Peter F. Buckley, MD introduces part 1 of our Special Report on schizophrenia.

Two compelling case reports provide additional evidence for potential mechanistic associations between the immune system and schizophrenia.

Antipsychotic drugs are the cornerstone in the management of psychotic disorders, but most patients fail to have a “good” response in short-term trials. Alternative strategies are presented here.

The incidence of suicidal ideation and self-harm behavior increases rapidly during adolescence and represents a period of heightened suicide risk.

Finding meaning helps to reframe the experiences of our own lives, not as events to hide in shame or guilt, but as experiences that made us physicians we are today.

Although psychiatrists may be better trained to treat suicidal patients, most patients with suicidal ideation are receiving care outside of specialty psychiatric settings and can benefit from interventions in primary care.

More than a slogan, the zero suicide approach applies evidence about what works in the detection, treatment, and management of individuals with intense suicidality.

Determining how to ensure delivery of excellent care while balancing medicolegal demands may seem to be an impossible task. When done in a collaborative way, safety planning can help the clinician better understand risk and targets for intervention.

Even while attitudes are opening up about mental health and suicide prevention, the rate of suicide continues to rise in the United States.

Combining clinical wisdom, skill, and knowledge may allow us to shift the trend toward increasing suicide rates and provide care that helps youths build lives they want to live.

This article provides a brief synopsis of the research regarding the use of psychotherapy to manage suicidal behavior, followed by several examples of strategies that such treatment employs.

This Special Report offers insight into gender vulnerabilities and clinical implications in areas like schizophrenia, Alzheimer dementia, and anxiety disorders.

A deep dive into how schizophrenia affects men versus women.

Clinicians can help raise awareness of the role of sex hormones in persistent anxiety by integrating 5 considerations into their practice.

Several misconceptions exist about the study of sex and gender in the AD field. The initial focus of this article is on whether women are at greater risk.

Dependence on alcohol and tobacco or illicit drugs is generally higher in men, but the gender gap is narrowing at an alarming rate, especially in adolescents.

Sleep difficulties and sleep disorders are the most common comorbidities reported in individuals with ADHD. Careful assessment will lead to helpful interventions.

ADHD can present with symptoms such as irritability, mood lability, low frustration tolerance and low self-esteem, making it easily confused with mood disorders and personality disorders.

These three recent trends in ADHD neuroimaging may lead to objective tools for diagnosis as well as stimulate discovery of novel therapeutics.

This collection brings together topics on trauma and stress that are neglected in the current literature.

As we shift from treating disease and toward supporting health, medication is merely one possible intervention in a spectrum of possible ones.

Cognitive problems have historically been the last to be recognized and treated in the clinical setting.

In this two-part Special Report, the authors provide evidence-based information to guide our assessment, diagnosis, and treatment of ADHD across the lifespan.

This article examines the contributory role of diet on ADHD symptoms, including how the elimination of certain foods and additives, as well as the consumption of other foods or nutrients, may impact symptoms.

Despite the proven efficacy and safety of medications for ADHD, abuse is a growing concern.

Mental health stigma has been found to be a significant factor in African-American treatment engagement. For this reason, taking steps to understand cultural considerations is key.

Given the severe burden, grave suffering, and lack of remission with standard therapeutics in many patients with PTSD, preliminary data on the role of ECT seems promising.

Trauma may be a hidden variable in the lives of older adults, impacting them in ways they may not recognize or be willing to admit.