Psychopharmacology

This Special Report on treatment resistance provides expert guidance on how to treat patients who are still unresponsive after multiple unsuccessful attempts at intervention for some common mental disorders.

Trauma-focused cognitive-behavioral therapy, pharmacotherapy, and combinations thereof. Expert guidance here.

While treatment of bipolar disorder challenging , the notion that it is treatment resistant is contradicted by longitudinal and treatment research that indicates high rates of remission over time, moderate rates of recovery, and significant response to structured treatments tailored to symptoms.

This article focuses on treatment resistance to medications in adult male and non-pregnant adult female outpatients with any type of DSM-5 diagnosed bipolar disorder.

Recommendations from an international panel of experts on the management of MDD.

Treatment nonadherence in psychiatric patients contributes to increased suicide rates, illness exacerbation, hospitalization, and mortality. This Special Report countdown highlights the psychiatrist’s role in addressing barriers to treatment in a number of scenarios.

New evidence bolsters the reputation of clozapine as the “gold-standard” antipsychotic for patients with treatment-resistant schizophrenia.

The authors outline a series of strategies that can help promote adherence to the therapeutic regimen.

Is an effective, well-tolerated treatment for the negative symptoms of schizophrenia on the horizon?

This article delineates the role of psychiatrists in preventing HIV transmission before and after HIV exposure through pre- and post-exposure prophylaxis.

Neither time nor science has given pause to some attorneys who exploit the misunderstanding that surrounds the putative "criminogenic" effects of antidepressants.

This article focuses on appropriate versus inappropriate use of antipsychotics, the importance of careful assessment, and the consequences of not treating.

MAOIs deserve special consideration in the treatment of refractory depression. Here's a case in point.

New findings support the involvement of microbiota alterations in psychosis-and point to novel treatments.

Which psychotropic combinations unlock the door to successful treatment?

Do prolactin-elevating antipsychotics put women at risk for endometrial cancer?

This article explores how motivational pharmacotherapy and motivational enhancement therapy can galvanize depressed patients to get well.

Here: a plethora of treatment options, including mood-lifting stabilizers, non-antidepressants, psychotherapy, and lifestyle interventions.

Which of these agents best prevents relapse? A recent study employed a novel approach to find out.

How widely used is this “gold-standard” antipsychotic?

Appropriate use of benzodiazepines in patients with a substance use disorder is an important skill. Here are some important considerations.

If larger trials confirm the strong antidepressant effects observed so far, botulinum toxin may become a standard therapeutic addition to the psychiatric armamentarium.

In Get Out, director/writer Justin Peele’s provocative debut, the bodies snatched are African American (mostly robust males); the cannibals of consciousness are white residents of an affluent Baltimore suburb, where the living is easy and the politics fashionably progressive.

An overview of the DSM diagnostic system, the medicalization of normal variants of human behavior, and physician-assisted suicide.

Here's why psychiatrists and other mental health professionals need to understand the relationship between cannabis and mental disorders.